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Pharma Collaborations

Expression Pathology offers an extensive menu of assays measuring actual protein expression in standard clinical FFPE tissue samples. They can be used for both targeted drug development and patient stratification needs. The assays can be multiplexed and used for both preclinical and clinical studies. The assays measure the presence of the functional proteins in the tissue sample — not the expression of the gene.

GLP SRM Pharma Assay/Plex Menu: High interest Targeted Assays
Quantitative SRMs Analytical SRMs (Relative Data)

Onco-plex

  • EGFR
  • HER2
  • trunc HER2
  • HER3
  • cMET
  • IGF-1R
  • cSRC
  • BIM
  • SPARC
  • EPHA2
  • DR5

Phospho-plex

  • pEGFR


  • pHER3
  • pMET

  • pSRC

  • pMEK
  • pERK
  • p70S6K


Signaling

  • pIGF-1R
  • IRS-1
  • pHER2
  • p110a
  • pAKT

Breast-Plex

  • Ki67
  • ER
  • PR

Housekeeping

  • HSP90A
  • HSP90B
  • GSK3β
  • Actin B


Warburg-plex

  • Cav-1
  • PGK1
  • PKM2
  • LDHA
  • TPI
  • PMI
  • FBPA
  • Enolase
  • GAPDH


Adeno/SCC-plex

  • Keratin 7
  • Keratin 5
  • Keratin 14
  • Keratin 15
  • Keratin 13
  • Keratin 19

EMT-plex

  • E-Cadherin
  • β-Catenin
  • Vimentin
  • S100A4 N
  • Cadherin

Contact us to discuss how we can work together in areas that complement your own internal needs, resources and expertise.

Studies performed at Expression Pathology adhere to the Good Laboratory Practice regulations set forth by the FDA (21 CFR Part 58).