Expression Pathology Inc. (EPI) is a private biotechnology company leading
the development of innovative tissue protein analysis methods for
research and diagnostic applications. Our patented
Liquid Tissue® sample preparation and Director® laser microdissection
technologies are opening new ways to extract valuable protein information
from tissue.
Focusing on the gold standard in clinical tissue preservation, formalin-fixed
paraffin-embedded (FFPE) tissue, we are developing targeted tissue proteomic assays.
Our technology has great potential in drug development, clinical
trials and personalized
medicine. Measuring protein expression in standard formalin-fixed
tissue samples can provide diagnostic and prognostic information
to guide treatment decisions.
FFPE tissue samples are routinely collected,
tested and archived in medical treatment and research facilities.
They constitute
a huge untapped resource for discovery, validation and accurate
measurement of biomarkers of disease progression and recurrence,
drug response and
toxicity.
Liquid Tissue technology is protected by U.S. Patent 7,473,532 and patents
pending and foreign equivalents thereof.
DIRECTOR technology is protected by U.S. Patents 7,294,367 and 7,381,440
and foreign equivalents thereof.
Expression Pathology Inc. is a leader in tissue proteomics.
Using our tissue
analysis platform we are developing targeted tissue proteomic assays for oncology. The tests will provide information to guide treatment decisions – the
presence of protein drug targets, or which biological pathways are
activated in tumors to aid prognosis and drug selection.
Our scientists have extensive experience in pathology,
proteomics and tissue analysis. Call us to discuss your project. We can
help you design your experiment, and we can also help you with grant
writing.
The Liquid Tissue® MS protocol prepares FFPE samples
for mass spec analysis. Complete solubilization captures the entire protein
content. Mass spec friendly. Requires only 30,000 cells for multiple
mass spectrometry analyses.
The Director® Laser Microdissection Slides
provide the fastest, easiest and most accurate way
to collect specific cellular features from tissue sections. Engineered
for use with existing
Leica LMD and PALM Zeiss laser microdissection system.
Investors
We are seeking investments and collaboration opportunities.
For more information please contact our business development group.
b u s d e v @ e x p r e s s i o n p a t h o l o g y . c o m
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